Three-dimensional motion analysis of the hand and wrist is common in in-vitro and in-vivo biomechanical research. However, all studies rely on post testing analysis, where anatomical joint coordinate systems (JCS) are created to generate clinically relevant data to describe wrist motion. The purpose of this study was to present a comparison of four JCS that have been previously described in literature. Five cadaveric upper limbs were passively cycled through a flexion–extension and radial-ulnar deviation motion pathways using a wrist motion simulator. During testing, clinical wrist angle was measured using a goniometer. Following testing, wrist angle was calculated using four previously described methods of generating wrist coordinate systems, to facilitate their comparison. For flexion–extension wrist motion, only subtle difference between JCSs were detected. When comparing the performance of each JCS to the measured wrist angle during flexion–extension wrist motion, the RMSE for all three analyzed axes were all within 6.6°. For radial-ulnar deviation wrist motion, again only subtle difference between JCSs were detected. When comparing the performance of each JCS to the measured wrist angle during radial-ulnar deviation wrist motion, the RMSE for all three analyzed axes were all within 7.1°. The results of this coordinate system comparison do not favor one JCS generation method over another, as all were found to be similar and the small differences that were found are likely not clinically significant. We support using any of the analyzed coordinate system generation methods; however, a practical advantage of using certain methods is that the required digitized points to form the coordinate systems are palpable on the skin’s surface.

手和手腕的三维运动分析在体外和体内都很常见生物力学研究。但是，所有研究都依赖于测试后分析，即创建解剖学关节坐标系（JCS）来生成临床相关数据来描述腕部运动。这项研究的目的是对以前文献中描述的四个JCS进行比较。使用腕部运动模拟器，五个尸体上肢被动地通过屈伸和radial尺间偏斜运动路径循环。在测试过程中，使用测角仪测量了临床手腕角度。测试之后，使用前面描述的四种生成手腕坐标系的方法来计算手腕角度，以便于进行比较。对于屈伸腕运动，仅检测到JCS之间的细微差别。当将每个JCS的性能与屈伸手腕运动期间测得的腕角进行比较时，所有三个分析轴的RMSE均在6.6°之内。对于radial尺尺偏腕运动，再次仅检测到JCS之间的细微差别。当将每个JCS的性能与测得的腕尺向尺偏腕运动时的腕角进行比较时，所有三个分析轴的RMSE均在7.1°之内。这种坐标系比较的结果并不偏爱一种JCS生成方法，因为发现所有JCS生成方法都是相似的，并且发现的细微差别在临床上可能并不重要。我们支持使用任何分析的坐标系生成方法；然而，