Cinnamon, clove, and fennel are commonly used as spices and herbal medicines, and one of their medicinal uses is as aromatic stomachics. We investigated the effect on appetite in mice of inhaling volatile compounds contained in essential oils extracted from herbal medicines used as aromatic stomachics. The appetite-enhancing effects of cinnamon and fennel essential oils were similar to those of their main components trans-cinnamaldehyde and trans-anethole, respectively. The appetite-enhancing effects of clove essential oil were observed over a wide range of doses (4.5 × 10⁻⁴ to 4.5 × 10⁻³ mg/cage), even though the active compounds showed effects within a narrow range of doses (eugenol: 4.5 × 10⁻⁴ to 2.5 × 10⁻³ mg/cage; eugenol acetate: 1.1 × 10⁻³ to 4.5 × 10⁻³ mg/cage). The increase in appetite at doses that differed by tenfold in mice administered clove oil was due to synergistic effects between eugenol and eugenol acetate in clove oil. Thus, loss of appetite could be treated more effectively using essential oil containing both eugenol and eugenol acetate compared with the active compounds administered separately. Administering essential oils, such as cinnamon and clove, could improve loss of appetite without strict dosage adjustment.

中文翻译：

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吸入含有苯丙烷类似物的肉桂，丁香和茴香精油的食欲增强作用。

肉桂，丁香和茴香通常用作香料和草药，它们的医学用途之一是用作芳香胃药。我们研究了从用作芳香族胃药的草药中提取的香精油中所含挥发性化合物的吸入对小鼠食欲的影响。肉桂和茴香精油的食欲增强作用分别类似于其主要成分反式肉桂醛和反式茴香脑。 即使活性化合物在狭窄的剂量范围内也能显示出丁香精油的食欲增强作用，但剂量范围很广（4.5×10 ^-4至4.5×10 ^-3 mg / cage）。 4.5×10 ^-4至2.5×10^-3  mg /笼; 乙酸丁子香酚：1.1×10 ^-3至4.5×10 ^-3  mg /笼）。在服用丁香油的小鼠中，食欲的增加相差十倍，这是由于丁香油中丁子香酚和乙酸丁子香酚之间的协同作用所致。因此，与分别施用丁香酚和丁香酚的精油相比，与单独施用的活性化合物相比，食欲下降可以得到更有效的治疗。在不严格调整剂量的情况下，使用肉桂和丁香等精油可以改善食欲不振。