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Accessing alkyl boronic esters via visible light-mediated decarboxylative addition reactions of redox-active esters
Organic Chemistry Frontiers ( IF 5.4 ) Pub Date : 2020-06-17 , DOI: 10.1039/d0qo00440e
Xianli Shu 1, 2, 3, 4, 5 , Ruting Xu 1, 2, 3, 4, 5 , Qiang Ma 1, 2, 3, 4, 5 , Saihu Liao 1, 2, 3, 4, 5
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A general and facile approach for the synthesis of alkyl boronic esters via visible light-mediated decarboxylative radical addition of redox-active esters to vinyl boronic ester is presented. The reaction features mild, metal-free reaction conditions and broad substrate scope covering primary, secondary, and tertiary acids, as well as amino acids and drugs.

中文翻译:

通过可见光介导的氧化还原活性酯的脱羧加成反应获得烷基硼酸酯

提出了通过氧化还原活性酯到乙烯基硼酸酯的可见光介导的脱羧自由基加成合成烷基硼酸酯的通用且简便的方法。该反应具有温和,无金属的反应条件,并且底物范围广泛,涵盖伯,仲和叔酸以及氨基酸和药物。
更新日期:2020-07-28
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