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Risk factors for early and late recurrent ischemic strokes
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery Pub Date : 2020-06-17 , DOI: 10.1186/s41983-020-00190-3
Hassan Mohammed Elnady , Gharib Fawi Mohammed , Hazem Kamal Elhewag , Mohamed Khodery Mohamed , Ahmed Borai

Background Nationally, information regarding risk factors for early and late recurrence of ischemic stroke is limited. Objectives The aim of this study was to identify the risk factors for early and late recurrent ischemic stroke. Patients and methods We prospectively compared data from 58 patients with early (within 1 year after the index stroke) recurrent ischemic stroke with 64 patients with late (1 year or more after the index stroke) recurrent ischemic stroke. Patients in the study were admitted to the Department of Neurology and Psychological Medicine, Sohag University Hospital, in the period between April 2017 and August 2017. The etiology of recurrent stroke was determined according to the TOAST classification. The presence of vascular risk factors was registered and compared in both groups. Results Systolic blood pressure was significantly higher among those with late recurrence compared to those with early recurrence ( p = 0.026). Patients with early recurrent ischemic stroke were more likely to be aphasic ( p = 0.047). Regarding the TOAST classification, small vessel disease and undetermined etiology were significantly higher among patients with late recurrence, while cardioembolism and large artery atherosclerosis were significantly higher among those with early recurrence ( p = 0.008). Conclusion Patients with large artery atherosclerosis and cardioembolism are at increased risk of early recurrence and warrant special efforts for secondary prevention.

中文翻译:

早期和晚期复发性缺血性卒中的危险因素

背景 在全国范围内,关于缺血性卒中早期和晚期复发的危险因素的信息有限。目的 本研究的目的是确定早期和晚期复发性缺血性卒中的危险因素。患者和方法 我们前瞻性地比较了 58 名早期(指数卒中后 1 年内)复发性缺血性卒中患者和 64 名晚期(指数卒中后 1 年或更长时间)复发性缺血性卒中患者的数据。研究中的患者于2017年4月至2017年8月期间入住Sohag大学医院神经病学和心理医学科。根据TOAST分类确定复发性脑卒中的病因。记录并比较两组中血管危险因素的存在。结果晚期复发患者的收缩压显着高于早期复发患者(p = 0.026)。早期复发性缺血性卒中患者更可能失语(p = 0.047)。关于 TOAST 分类,晚期复发患者的小血管疾病和未确定病因显着更高,而早期复发患者的心源性栓塞和大动脉粥样硬化显着更高(p = 0.008)。结论 大动脉粥样硬化和心源性栓塞患者早期复发风险增加,需要特别努力进行二级预防。047)。关于 TOAST 分类,晚期复发患者的小血管疾病和未确定病因显着更高,而早期复发患者的心源性栓塞和大动脉粥样硬化显着更高(p = 0.008)。结论 大动脉粥样硬化和心源性栓塞患者早期复发风险增加,需要特别努力进行二级预防。047)。关于 TOAST 分类,晚期复发患者的小血管疾病和未确定病因显着更高,而早期复发患者的心源性栓塞和大动脉粥样硬化显着更高(p = 0.008)。结论 大动脉粥样硬化和心源性栓塞患者早期复发风险增加,需要特别努力进行二级预防。
更新日期:2020-06-17
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