An efficient and regioselective synthesis of fused polycyclic furo[3,4-c]indolo[2,1-a]isoquinolines through Rh(III)-catalyzed cascade C–H activation/annulation/lactonization of 2-arylindoles and 4-hydroxy-2-alkynoates has been developed. This cascade reaction displays high step economy and efficiency and tolerates various functional groups. The titled polycyclic furo[3,4-c]indolo[2,1-a]isoquinolines exhibit fluorescence emission.

中文翻译：

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通过Rh（III）催化的2-苯基吲哚与4-羟基-2-炔基酸酯的级联反应，一锅合成呋喃[3,4-c]吲哚并[2,1-a]异喹啉。

通过Rh（III）催化2-芳基吲哚和4-羟基-吲哚的级联C-H活化/环化/内酯化反应，可以高效，区域选择性地合成稠合的多环呋喃并[3,4- c ]吲哚并[ 2,1- a ]异喹啉。已经开发了2-链烷酸酯。该级联反应显示出高的步骤经济性和效率，并且可以耐受各种官能团。标题为多环呋喃并[3，4- c ]吲哚并[2，1- a ]异喹啉表现出荧光发射。