Glucosinolates (GSLs) are plant secondary metabolites comprising sulfur and nitrogen mainly found in plants from the order of Brassicales, such as broccoli, cabbage, and Arabidopsis thaliana. The activated forms of GSL play important roles in fighting against pathogens and have health benefits to humans. The increasing amount of data on A. thaliana generated from various omics technologies can be investigated more deeply in search of new genes or compounds involved in GSL biosynthesis and metabolism. This review describes a comprehensive inventory of A. thaliana GSLs identified from published literature and databases such as KNApSAcK, KEGG, and AraCyc. A total of 113 GSL genes encoding for 23 transcription components, 85 enzymes, and five protein transporters were experimentally characterized in the past two decades. Continuous efforts are still on going to identify all molecules related to the production of GSLs. A manually curated database known as SuCCombase (http://plant-scc.org) was developed to serve as a comprehensive GSL inventory. Realizing lack of information on the regulation of GSL biosynthesis and degradation mechanisms, this review also includes relevant information and their connections with crosstalk among various factors, such as light, sulfur metabolism, and nitrogen metabolism, not only in A. thaliana but also in other crucifers.

中文翻译：

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拟南芥中硫代葡萄糖苷生物合成途径的综合基因清单。

芥子油苷（GSLs）是植物次生代谢物，其包含硫和氮，主要存在于芸苔属植物中，例如西兰花，卷心菜和拟南芥。GSL的活化形式在对抗病原体方面起着重要作用，对人类健康有好处。从各种组学技术中获得的拟南芥数据的不断增加，可以进行更深入的研究，以寻找参与GSL生物合成和代谢的新基因或化合物。这篇评论描述了拟南芥的综合清单从已发表的文献和数据库（例如KNApSAcK，KEGG和AraCyc）中识别出GSL。在过去的二十年中，共有113种GSL基因编码了23种转录成分，85种酶和5种蛋白质转运蛋白。仍将继续努力寻找与GSL产生有关的所有分子。开发了一个手动管理的数据库，称为SuCCombase（http://plant-scc.org），可以用作全面的GSL库存。由于认识到缺乏有关GSL生物合成和降解机制调控的信息，该综述还包括相关信息及其与各种因素之间的串扰的联系，例如光，硫代谢和氮代谢，不仅在拟南芥中而且在其他方​​面十字军。