Abstract

Three new flavonoid glycosides, embeliaflavosides A-C (1–3), together with eight known flavonoid glycosides (4–11), were isolated from the fruits of Embelia ribes. Their structures were established based on the analyses of spectroscopic data. Compounds 1–11 were evaluated for antioxidant and α-glucosidase inhibitory activities. The results revealed that compounds 1–11 owned significant ABTS radical scavenging activity with IC₅₀ values of 2.52–9.78 µM, and DPPH scavenging activity with IC₅₀ values of 7.56–26.47 µM, respectively. However, α-glucosidase inhibition assay indicated that all the isolates were inactive.

摘要

从Embelia ribes的果实中分离出三种新的黄酮苷，即 embeliaflavosides AC ( 1-3 )，以及八种已知的黄酮苷 ( 4-11 ) 。它们的结构是基于光谱数据的分析建立的。评估了化合物1-11的抗氧化和α-葡萄糖苷酶抑制活性。结果表明，化合物1-11具有显着的ABTS自由基清除活性，IC ₅₀值为2.52-9.78 µM，DPPH清除活性的IC ₅₀值为7.56-26.47 µM。然而，α-葡萄糖苷酶抑制试验表明所有分离株均无活性。