Published as part of the Special Topic Recent Advances in Metal-Catalyzed Ring Construction

Abstract

A new visible-light-induced Ir(III)-catalyzed difluoroalkylation–bicyclization of 1,7-enynes with ethyl 2-bromo-2,2-difluoroacetate (BrCF₂CO₂Et) is described, furnishing a wide range of difluoromethyl-containing benzo[a]fluoren-5-ones in good to excellent yields. The reaction is operationally simple, proceeds with high efficiency under mild conditions, and shows excellent functional group compatibility.

中文翻译：

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铱（III）催化的二氟烷基化-可见光光氧化还原条件下1,7-烯炔向苯并[a]芴-5-酮的双环化

作为特别主题的一部分发表，金属催化环结构的最新进展

抽象

描述了一种新的可见光诱导的Ir（III）催化的2-溴-2,2-二氟乙酸乙酯（BrCF ₂ CO ₂ Et）对1,7-烯炔的二氟烷基化-双环化，提供了范围广泛的二氟甲基-含苯并[ a ]氟-5-酮，收率良好。该反应操作简单，在温和条件下高效进行，并且显示出优异的官能团相容性。