Acquired immunodeficiency syndrome (AIDS) was first described in 1981, and continues to be one of the worst global health pandemics in recorded history. Concerted international efforts have helped to increase awareness of human immunodeficiency (HIV) status, improve access to treatment and continuation of therapy to achieve viral suppression with a goal of ending the AIDS epidemic by 2030. The clinical outcomes for patients living with HIV on combined antiretroviral therapy are considerably improved with prolonged life expectancy and superior quality of life. Further, perinatal transmission rates have dramatically decreased with elimination of mother to child transmission of HIV in a growing number of countries worldwide. However, there have been significant reductions in the pace of progress in treatment expansion for pregnant women with failure to meet global targets in 2018. In this review, we will highlight recent advances and challenges ahead in 2020 for three areas of perinatal care for women with HIV in developed countries: (a) pregnancy planning considerations, (b) impact of antiviral medications on perinatal outcomes, and (c) infant feeding practices. The promise of a HIV‐free generation is on the horizon and continued international efforts in preventing perinatal transmission are an important component of this achievement.

中文翻译：

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孕妇 HIV 感染：2020 年更新

获得性免疫缺陷综合征 (AIDS) 于 1981 年首次被描述，并且仍然是有史以来最严重的全球健康流行病之一。协调一致的国际努力有助于提高对人类免疫缺陷 (HIV) 状况的认识，改善获得治疗的机会和继续治疗以实现病毒抑制，目标是到 2030 年结束艾滋病流行。 接受联合抗逆转录病毒治疗的 HIV 感染者的临床结果随着预期寿命的延长和生活质量的提高，治疗得到显着改善。此外，随着全世界越来越多的国家消除了艾滋病毒母婴传播，围产期传播率显着降低。然而，由于未能达到 2018 年的全球目标，孕妇治疗扩展的进展速度显着放缓。在本次审查中，我们将重点介绍 2020 年艾滋病毒感染者围产期护理的三个领域的最新进展和未来挑战发达国家：(a) 怀孕计划考虑，(b) 抗病毒药物对围产期结局的影响，以及 (c) 婴儿喂养做法。无艾滋病一代的承诺即将到来，而在预防围产期传播方面的持续国际努力是这一成就的重要组成部分。(b) 抗病毒药物对围产期结局的影响，以及 (c) 婴儿喂养做法。无艾滋病一代的承诺即将到来，而在预防围产期传播方面的持续国际努力是这一成就的重要组成部分。(b) 抗病毒药物对围产期结局的影响，以及 (c) 婴儿喂养做法。无艾滋病一代的承诺即将到来，而在预防围产期传播方面的持续国际努力是这一成就的重要组成部分。