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Combination of intramuscular alfaxalone, butorphanol, and midazolam as a novel immobilization protocol in 3 ring-tailed lemurs (Lemur catta).
Irish Veterinary Journal ( IF 2.9 ) Pub Date : 2020-06-16 , DOI: 10.1186/s13620-020-00163-1
Kyratsoula Pentsou 1 , Vilhelmiina Huuskonen 1
Affiliation  

There is very little data on the optimal anaesthetic management of ring-tailed lemurs, and the available information is mostly based on extrapolation from other species. In addition, a thorough pre-anaesthetic assessment of lemurs might not be possible without prior chemical immobilization, making a safe immobilization protocol essential. Three ring-tailed lemurs (Lemur catta) were immobilized using a combination of intramuscular alfaxalone (5 mg/kg), butorphanol (0.2 mg/kg), and midazolam (0.2 mg/kg), at the University College Dublin Veterinary Hospital. One lemur was anaesthetised once, two lemurs twice, amounting to five anaesthetic events. Conversion to general anaesthesia was warranted in all five occasions, and anaesthesia was maintained with either sevoflurane in oxygen or alfaxalone infusion. The immobilization protocol provided an adequate duration of deep sedation for diagnostic procedures and in some occasions allowed the intubation of the trachea. Analgesia was also provided for minor procedures. No major complications were noted with the protocol used. The combination of intramuscular alfaxalone, butorphanol and midazolam provided a clinically useful sedation/immobilization in ring-tailed lemurs with only minor complications such as mild hypothermia, hypotension, hypoventilation and bradycardia. This protocol could be considered in ring-tailed lemurs that need to be immobilized for minor procedures, or as a pre-anaesthetic premedication, especially if a full pre-anaesthetic clinical exam is not possible.

中文翻译:

肌肉注射阿法沙龙、布托啡诺和咪达唑仑作为 3 只环尾狐猴 (Lemur catta) 的新型固定方案。

关于环尾狐猴最佳麻醉管理的数据很少,可用信息主要基于其他物种的推断。此外,如果没有事先进行化学固定,可能无法对狐猴进行彻底的麻醉前评估,因此安全的固定方案必不可少。在都柏林大学兽医医院,使用肌肉注射阿法沙龙 (5 mg/kg)、布托啡诺 (0.2 mg/kg) 和咪达唑仑 (0.2 mg/kg) 的组合固定了三只环尾狐猴 (Lemur catta)。一只狐猴被麻醉一次,两只狐猴被麻醉两次,共计五次麻醉事件。所有五次都需要转为全身麻醉,并使用七氟醚氧气或阿法沙龙输注维持麻醉。固定方案为诊断程序提供了足够的深度镇静持续时间,并且在某些情况下允许气管插管。还为小程序提供了镇痛剂。使用的方案没有发现重大并发症。肌肉注射阿法沙酮、布托啡诺和咪达唑仑的组合在环尾狐猴中提供了临床上有用的镇静/固定,只有轻微的并发症,例如亚低温、低血压、通气不足和心动过缓。该方案可用于需要固定以进行小手术的环尾狐猴,或作为麻醉前用药,特别是在无法进行全面麻醉前临床检查的情况下。还为小程序提供了镇痛剂。使用的方案没有发现重大并发症。肌肉注射阿法沙酮、布托啡诺和咪达唑仑的组合在环尾狐猴中提供了临床上有用的镇静/固定,只有轻微的并发症,例如亚低温、低血压、通气不足和心动过缓。该方案可用于需要固定以进行小手术的环尾狐猴,或作为麻醉前用药,特别是在无法进行全面麻醉前临床检查的情况下。还为小程序提供了镇痛剂。使用的方案没有发现重大并发症。肌肉注射阿法沙酮、布托啡诺和咪达唑仑的组合在环尾狐猴中提供了临床上有用的镇静/固定,只有轻微的并发症,例如亚低温、低血压、通气不足和心动过缓。该方案可用于需要固定以进行小手术的环尾狐猴,或作为麻醉前用药,特别是在无法进行全面麻醉前临床检查的情况下。布托啡诺和咪达唑仑在环尾狐猴中提供了临床上有用的镇静/固定,只有轻微的并发症,如轻度低温、低血压、通气不足和心动过缓。该方案可用于需要固定以进行小手术的环尾狐猴,或作为麻醉前用药,特别是在无法进行全面麻醉前临床检查的情况下。布托啡诺和咪达唑仑在环尾狐猴中提供了临床上有用的镇静/固定,只有轻微的并发症,如轻度低温、低血压、通气不足和心动过缓。该方案可用于需要固定以进行小手术的环尾狐猴,或作为麻醉前用药,特别是在无法进行全面麻醉前临床检查的情况下。
更新日期:2020-06-16
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