当前位置: X-MOL 学术Rejuvenation Res. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A Call for a Three-Tiered Pandemic Public Health Strategy in Context of SARS-CoV-2.
Rejuvenation Research ( IF 2.6 ) Pub Date : 2020-06-16 , DOI: 10.1089/rej.2020.2363
Brian P Hanley 1 , Steve Keen 2 , George Church 3
Affiliation  

The twin impacts of pandemic disease and severe economic repercussions of lockdown have led us to call for creation of a rapid vaccine rollout infrastructure to support medicine which is the front line of biodefense. There will be other, and worse pandemics to come, some of which are likely to be man-made. So we need increased surveillance of both human and animal diseases. We also call for recognition that economic damage can be as great as, or more severe than, the pandemic itself, which needs to be taken into account when weighing risk of withholding vaccines. We discuss how in the modern world, we know enough to make and deploy safe vaccines in as little as a few weeks. There are multiple types of vaccines now, and each type should be handled differently. We have nucleotide (RNA & DNA), component protein, killed, whole killed, live recombinant, and live attenuated vaccines today. Particularly in a crisis, nucleotide vaccines can be released immediately. Component, killed, and whole killed can also be rolled out rapidly. Live vaccines can be examined and released much more quickly than they are. This is not 1955, we know far more about vaccines and immunology today. For those advocating for increased longevity, pandemic response strategy is as important as any possible treatments to extend life span. #ReleaseTheVacc

中文翻译:

在SARS-CoV-2的背景下呼吁制定三层大流行性公共卫生策略。

大流行性疾病和封锁造成的严重经济影响的双重影响使我们呼吁建立快速的疫苗推出基础设施,以支持作为生物防御的前线的药物。还会有其他甚至更严重的流行病出现,其中一些很可能是人为造成的。因此,我们需要加强对人类和动物疾病的监视。我们还呼吁人们认识到,经济损失可能与大流行本身一样大或更严重,在权衡扣留疫苗的风险时需要考虑到这一点。我们讨论了在现代世界中,我们如何在短短几周内就足以制造和部署安全疫苗的知识。现在有多种类型的疫苗,每种类型的疫苗应以不同的方式处理。我们有核苷酸(RNA和DNA),成分蛋白,被杀死,被完全杀死,活重组和减毒活疫苗。特别是在危机中,核苷酸疫苗可以立即释放。也可以快速推出已杀死的组件和全部被杀死的组件。活疫苗的检查和发布速度比以往快得多。现在不是1955年,我们今天对疫苗和免疫学的了解更多。对于那些主张延长寿命的人来说,大流行应对策略与延长寿命的任何可能的治疗方法一样重要。#ReleaseTheVacc 对于那些主张延长寿命的人来说,大流行应对策略与延长寿命的任何可能的治疗方法一样重要。#ReleaseTheVacc 对于那些主张延长寿命的人来说,大流行应对策略与延长寿命的任何可能的治疗方法一样重要。#ReleaseTheVacc
更新日期:2020-06-16
down
wechat
bug