Introduction. The management of neuropathic pain remains complex, generally because of the psychiatric comorbidity that is often underdiagnosed. The objectives of our work were to determine the link between depression and the characteristics of NP on the one hand and quality of life on the other hand, in a sample of subjects consulting for neuropathic pain (NP) regardless of etiology. Methods. We conducted a cross-sectional study involving 61 neuropathic pain consulting patients in whom we assessed five parameters, namely, neuropathic pain based on DN4, pain intensity using EVA, anxiety, and depression according to the HADS and quality of life. Results. The study population mean age was 52.71 ± 14.29 years while the sex ratio (m/f) was 0.52. The neuropathic pain’s most common etiologies were postherpetic pain, carpal tunnel syndrome, and diabetic neuropathy. Depression and anxiety prevailed by 65.6% and 73.7%, respectively. The quality of life was impaired with average SF-12 physical and mental scores of 33.76 ± 8.03 and 37.78 ± 11.52, respectively. The overall mean BPI score was 5.53 ± 1.76. Patients with high DN4 scores were significantly more depressed (). A significantly positive association was found between the depression score and the pain intensity (, r = 0.41). Depressed subjects had a poor quality of life according to SF-12 and BPI. Conclusion. Given the depressive comorbidity impact on the neuropathic pain components as well as the quality of life, screening for this comorbidity should be part of the baseline ND assessment.

中文翻译：

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神经性疼痛中抑郁症的患病率及其对生活质量的影响。

介绍。神经性疼痛的治疗仍然很复杂，通常是因为精神科合并症经常被诊断不足。我们工作的目标是，在不考虑病因的神经性疼痛 (NP) 咨询受试者样本中，一方面确定抑郁症与 NP 特征之间的联系，另一方面与生活质量之间的联系。方法。我们进行了一项横断面研究，涉及 61 名神经性疼痛咨询患者，我们评估了五个参数，即基于 DN4 的神经性疼痛、使用 EVA 的疼痛强度、根据 HADS 和生活质量的焦虑和抑郁。结果。研究人群平均年龄为 52.71 ± 14.29 岁，性别比（男/女）为 0.52。神经性疼痛最常见的病因是带状疱疹后痛、腕管综合征和糖尿病神经病变。抑郁和焦虑的比例分别为 65.6% 和 73.7%。生活质量受到损害，平均 SF-12 身体和心理评分分别为 33.76 ± 8.03 和 37.78 ± 11.52。总体平均 BPI 得分为 5.53 ± 1.76。DN4 评分高的患者明显更抑郁（）。抑郁评分与疼痛强度之间存在显着正相关（， r  = 0.41）。根据 SF-12 和 BPI，抑郁症受试者的生活质量较差。结论。鉴于抑郁性合并症对神经性疼痛成分以及生活质量的影响，这种合并症的筛查应成为基线 ND 评估的一部分。