To evaluate trends related to accidental overdose deaths in Oklahoma, with a focus on opioids and methamphetamine. All accidental drug overdose deaths in the state of Oklahoma from 2002 to 2017 were reviewed. Opioids were grouped into the following categories: all opioids, prescription opioids, synthetic opioids and heroin. Age-adjusted death rates for methamphetamine and each opioid category were calculated and analyzed. Accidental overdoses accounted for 9,936 deaths during the study period. Of these, opioids were seen in 62.9%, with prescription opioids comprising 53.8%, synthetic opioids 10.3% and heroin 2.8%. Synthetic opioids, despite a recent upward nationwide trend, showed a slight overall decrease (−6.8%) from 2009 to 2017. In contrast, methamphetamine showed a 402.2% increase from 2009 to 2017 and an overall increase of 1,526.7%. Methamphetamine was involved in the most overdoses (1,963), followed by oxycodone (1,724). Opioid-related deaths were most common among white individuals (90.3%) and showed a slight male predilection (56.9%). With the intent of assessing the opioid epidemic as it relates to accidental overdoses in Oklahoma, this study suggests that opioid-related overdoses have slowed in recent years amidst a sharp increase in methamphetamine deaths.

中文翻译：

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2002-2017年俄克拉荷马州的药物过量死亡：阿片类药物和甲基苯丙胺趋势。

为了评估与俄克拉何马州药物过量死亡相关的趋势，重点是阿片类药物和甲基苯丙胺。回顾了2002年至2017年俄克拉荷马州的所有药物过量死亡事故。阿片类药物分为以下几类：所有阿片类药物，处方阿片类药物，合成阿片类药物和海洛因。计算并分析了甲基苯丙胺和每种阿片类药物的年龄调整死亡率。在研究期间，意外用药过量导致9,936人死亡。其中，阿片类药物占62.9％，处方阿片类药物占53.8％，合成阿片类药物占10.3％，海洛因占2.8％。尽管全国范围内合成阿片类药物近期呈上升趋势，但从2009年至2017年总体略有下降（-6.8％）。相反，甲基苯丙胺从2009年至2017年增长402.2％，总体增长1,526.7％。甲基苯丙胺是最过量的（1,963），其次是羟考酮（1,724）。阿片类药物相关的死亡最常见于白人（90.3％），男性偏爱轻微（56.9％）。出于评估与俄克拉何马州意外过量相关的阿片类药物流行的趋势，这项研究表明，近年来，随着甲基苯丙胺死亡人数的急剧增加，与阿片类药物相关的药物过量减缓了速度。