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Understanding SARS-CoV-2-related multisystem inflammatory syndrome in children.
Nature Reviews Immunology ( IF 100.3 ) Pub Date : 2020-06-16 , DOI: 10.1038/s41577-020-0367-5
Anne H Rowley 1, 2, 3
Affiliation  

A new multisystem inflammatory syndrome apparently related to infection with SARS-CoV-2 has recently been reported in older children (known as MIS-C), manifested by severe abdominal pain, cardiac dysfunction and shock. Here, I discuss the similarities and differences between MIS-C and Kawasaki disease, focusing on their epidemiology, aetiology and pathophysiological mechanisms. In this Comment, Anne Rowley discusses what we know so far about the recently described multisystem inflammatory syndrome in older children associated with SARS-CoV-2 infection and how it differs from Kawasaki disease.

中文翻译:

了解儿童的SARS-CoV-2相关多系统炎症综合征。

最近,在较大的儿童中(据称为MIS-C),出现了一种新的与SARS-CoV-2感染明显相关的新型炎症综合征,表现为严重的腹痛,心脏功能障碍和休克。在这里,我将讨论MIS-C与川崎病之间的异同,重点是它们的流行病学,病因学和病理生理机制。在本评论中,安妮·罗利(Anne Rowley)讨论了我们到目前为止对与SARS-CoV-2感染相关的大龄儿童最近描述的多系统炎症综合症的了解,以及它与川崎病的区别。
更新日期:2020-06-16
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