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Taste and Smell Impairment in SARS-CoV-2 Recovers Early and Spontaneously: Experimental Data Strongly Linked to Clinical Data.
ACS Chemical Neuroscience ( IF 5 ) Pub Date : 2020-06-15 , DOI: 10.1021/acschemneuro.0c00296
Ibrahim Sayin 1 , Zahide Mine Yazici 1
Affiliation  

A growing body of literature indicates that smell and taste impairment has frequently occurred during the Severe Acute Respiratory Syndrome (SARS)-like Coronavirus (SARS-CoV-2) outbreak. Experimental studies have mostly found that non-neural-type cells are responsible for SARS-CoV-2-related taste and smell impairment. If this is the case, smell/taste impairment needs to recover early. Literature data from clinical studies indicated a strong correlation between experimental and clinical findings. This article presents clinical studies related to SARS-CoV-2-induced smell/taste impairment that reported recovery rates. Experimental researchers may use these data to observe the dynamics of smell impairment and implement these findings in their research (e.g., correct timing of sampling) to perform further studies.

中文翻译:

SARS-CoV-2 的味觉和嗅觉障碍早期自发恢复:实验数据与临床数据密切相关。

越来越多的文献表明,在严重急性呼吸系统综合症(SARS)样冠状病毒(SARS-CoV-2)爆发期间,嗅觉和味觉障碍经常发生。实验研究大多发现非神经型细胞导致 SARS-CoV-2 相关的味觉和嗅觉障碍。如果是这种情况,嗅觉/味觉障碍需要尽早恢复。临床研究的文献数据表明实验和临床结果之间存在很强的相关性。本文介绍了与 SARS-CoV-2 引起的嗅觉/味觉障碍相关的临床研究,并报告了恢复率。实验研究人员可以使用这些数据来观察嗅觉障碍的动态,并将这些发现应用到他们的研究中(例如,正确的采样时间)以进行进一步的研究。
更新日期:2020-07-15
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