Depression is common in patients with chronic heart failure (CHF) and is a predictor of rehospitalization and mortality. However, the complex bidirectional relationships between these two conditions are barely understood. We investigated the course of depression and markers of CHF (New York Heart Association [NYHA] functional class, N‐terminal‐prohormone B‐type natriuretic peptide [NT‐proBNP], and left ventricular ejection fraction [LVEF]) in a longitudinal study over a period of 2 years, using three assessment points.

中文翻译：

---

抑郁与慢性心力衰竭指标之间双向关系的交叉滞后分析。

抑郁症在慢性心力衰竭（CHF）患者中很常见，并且是重新住院和死亡率的预测指标。但是，这两个条件之间的复杂双向关系几乎是未知的。在一项纵向研究中，我们调查了抑郁症的病程和CHF的标志物（纽约心脏协会[NYHA]功能类别，N端激素B型利尿钠肽[NT-proBNP]和左室射血分数[LVEF]）在2年的时间内，使用三个评估点。