PURPOSE POTS patients undergo labial salivary gland biopsies (LSGB) for histologic confirmation of Sjogren's syndrome (SS). Predictive features of positive results are unknown. METHODS 161 POTS patients underwent LSGB. Their charts were reviewed for antibody and diagnostic testing results. RESULTS Only 11% (17/161) of POTS patients were SS positive. There were more positive ANA antibodies in those with positive LSGB (65% v 28%, p = .0026). Positive skin nerve biopsy for small fiber neuropathy (SFN) was associated with positive LSGB (p = .046). CONCLUSION A positive ANA and skin biopsy for SFN are two helpful features in selecting POTS patients for LSGB.

中文翻译：

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唾液腺活检在 POTS 患者群体中诊断干燥综合征的效用

目的 POTS 患者接受唇唾液腺活检 (LSGB) 以进行干燥综合征 (SS) 的组织学确认。阳性结果的预测特征是未知的。方法 161 名 POTS 患者接受了 LSGB。对他们的图表进行了抗体和诊断测试结果的审查。结果 只有 11% (17/161) 的 POTS 患者为 SS 阳性。LSGB 阳性者的 ANA 抗体阳性率更高（65% 对 28%，p = .0026）。小纤维神经病变 (SFN) 的皮肤神经活检阳性与 LSGB 阳性相关 (p = .046)。结论 ANA 阳性和 SFN 皮肤活检是为 LSGB 选择 POTS 患者的两个有用特征。