The effect of basic process conditions and the initial distribution of mixed liquids on mixing on the molecular scale was studied experimentally for helical and twisted bends reactors. The selectivity of two competitive-parallel reactions, acid-base neutralization and alkaline ester hydrolysis, carried out in aqueous solutions between initially unmixed reactants, was used to quantify micromixing in steady-state, isothermal and laminar flow. Faster micromixing is achieved in the twisted bends mixer than in the helical mixer due to the periodic reorientation of Dean vortices, present in curved conduits. The difference in micromixing performance of the two reactors decreases for high Reynolds numbers (Re > 1000) when ester hydrolysis is no longer controlled by mixing. Micromixing for lower Reynolds numbers can be improved by changing the ratio of volumetric flows of the reactant solutions and by using a distribution head, which at the reactor entrance creates the contact surface between mixed liquids perpendicular to the curvature plane of the first pipe bend. When micromixing in the reactor becomes so slow that the final selectivity approaches its maximum value, changing the ester to a slower reacting one helps to adjust the sensitivity of the test reaction system to the deteriorating mixing conditions.

通过实验研究了螺旋和扭曲弯管反应器的基本工艺条件和混合液体的初始分布在分子尺度上对混合的影响。在最初未混合的反应物之间的水溶液中进行的两个竞争性平行反应（酸碱中和和碱性酯水解）的选择性用于量化稳态，等温和层流中的微混合。由于弯曲导管中存在的迪安涡旋的周期性重新定向，在扭曲弯头混合器中比在螺旋混合器中实现了更快的微混合。对于高雷诺数，两个反应器的微混合性能差异减小（Re > 1000）时，不再通过混合控制酯水解。可以通过更改反应物溶液的体积流量比率和使用分配头来改善低雷诺数的微混合，该分配头在反应器入口处形成垂直于第一弯管曲率平面的混合液体之间的接触面。当反应器中的微混合变得如此缓慢以至于最终选择性接近其最大值时，将酯改为反应速度较慢的酯有助于调整测试反应系统对恶化的混合条件的敏感性。