A formal amide insertion and substitution reaction for the synthesis of functionalized isoindolin-1-ones was developed on the basis of graphene oxide (GO) as a green and oxidant-acid bifunctional carbon material. A series of N-acylisoindolin-1-ones were synthesized in good to excellent yields directly from benzoisofurans and nitriles in the presence of GO without the need for any additives or metals.

中文翻译：

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氧化石墨烯：一种绿色的氧化剂-酸双功能碳材料，用于通过酰胺的正式插入和取代来合成功能化的异吲哚啉-1-酮

在作为绿色和氧化剂-酸双功能碳材料的氧化石墨烯（GO）的基础上，开发了用于合成官能化异吲哚啉-1-酮的正式酰胺插入和取代反应。在GO的存在下，不需要任何添加剂或金属，直接从苯并异呋喃和腈合成了一系列N-酰基异吲哚啉-1-酮，产率高至优异。