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Resource: A multi-species multi-timepoint transcriptome database and webpage for the pineal gland and retina.
Journal of Pineal Research ( IF 10.3 ) Pub Date : 2020-06-13 , DOI: 10.1111/jpi.12673
Eric Chang 1 , Cong Fu 2, 3, 4, 5 , Steven L Coon 2, 6 , Shahar Alon 7 , Marjan Bozinoski 8 , Matthew Breymaier 9 , Diego M Bustos 2 , Samuel J Clokie 2 , Yoav Gothilf 7 , Caroline Esnault 1 , P Michael Iuvone 10 , Christopher E Mason 8 , Margaret J Ochocinska 2 , Adi Tovin 7 , Charles Wang 11 , Pinxian Xu 12 , Jinhang Zhu 13, 14 , Ryan Dale 1 , David C Klein 2, 15
Affiliation  

The website and database https://snengs.nichd.nih.gov provides RNA sequencing data from multi‐species analysis of the pineal glands from zebrafish (Danio rerio), chicken (White Leghorn), rat (Rattus novegicus), mouse (Mus musculus), rhesus macaque (Macaca mulatta), and human (Homo sapiens); in most cases, retinal data are also included along with results of the analysis of a mixture of RNA from tissues. Studies cover day and night conditions; in addition, a time series over multiple hours, a developmental time series and pharmacological experiments on rats are included. The data have been uniformly re‐processed using the latest methods and assemblies to allow for comparisons between experiments and to reduce processing differences. The website presents search functionality, graphical representations, Excel tables, and track hubs of all data for detailed visualization in the UCSC Genome Browser. As more data are collected from investigators and improved genomes become available in the future, the website will be updated. This database is in the public domain and elements can be reproduced by citing the URL and this report. This effort makes the results of 21st century transcriptome profiling widely available in a user‐friendly format that is expected to broadly influence pineal research.

中文翻译:

资源:松果体和视网膜的多物种多时间点转录组数据库和网页。

网站和数据库 https://snengs.nichd.nih.gov 提供来自斑马鱼 ( Danio rerio )、鸡 (White Leghorn)、大鼠 ( Rattus nove gicus )、小鼠 ( Mus musculus)、恒河猴(Macaca mulatta)和人类(Homo sapiens); 在大多数情况下,还包括视网膜数据以及来自组织的 RNA 混合物的分析结果。研究涵盖白天和黑夜条件;此外,还包括多个小时的时间序列、发育时间序列和大鼠药理学实验。使用最新的方法和组件对数据进行了统一的重新处理,以便在实验之间进行比较并减少处理差异。该网站提供搜索功能、图形表示、Excel 表格和所有数据的跟踪中心,以便在 UCSC 基因组浏览器中进行详细可视化。随着从研究人员那里收集到更多数据以及将来可以使用改进的基因组,该网站将进行更新。该数据库属于公共领域,可以通过引用 URL 和本报告来复制元素。
更新日期:2020-06-13
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