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A heat-generating lithium-ferrite doped bioactive glass for cancer hyperthermia
Physica B: Condensed Matter ( IF 2.8 ) Pub Date : 2020-06-12 , DOI: 10.1016/j.physb.2020.412298
A. Yazdanpanah , F. Moztarzadeh , S. Arabyazdi

In this study, lithium-ferrite bioactive glasses were prepared through the sol-gel technique. To evaluate the possible use of prepared bioactive glasses in hyperthermia therapy, the structural and magnetic properties of the glasses were characterized. The morphology and composition of the glasses were evaluated using SEM, XRD, and TEM methods. Laser particle size analyzer (LPSA) was used to study the glass particles’ sizes. The final synthesis temperature was determined using DTA. To estimate the magnetic properties, the VSM and Calorimetric analysis were used. The results of VSM and calorimetric analysis showed that the magnetic properties of samples improve as the magnetic portion increases. As shown in the results, the bioactive glasses can provide up to 47.2 °C for cancer hyperthermia. LPAS results showed the particles sizes are in the range of 35–85 nm. Conclusively, this research has demonstrated that synthesized glasses are the most promising candidates in cancer therapy using hyperthermia.



中文翻译:

用于癌症热疗的生热掺锂铁氧体生物活性玻璃

在这项研究中,通过溶胶凝胶技术制备了铁酸锂生物活性玻璃。为了评估制备的生物活性玻璃在热疗中的可能用途,对玻璃的结构和磁性进行了表征。使用SEM,XRD和TEM方法评估了玻璃的形态和组成。激光粒度分析仪(LPSA)用于研究玻璃颗粒的尺寸。最终合成温度使用DTA确定。为了评估磁性,使用了VSM和量热分析。VSM和量热分析的结果表明,样品的磁性随磁性部分的增加而提高。如结果所示,生物活性玻璃最多可提供47.2°C用于癌症热疗。LPAS结果表明,粒径在35-85 nm之间。最终,这项研究表明,合成玻璃是使用高热疗法进行癌症治疗的最有希望的候选者。

更新日期:2020-06-12
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