The fresh water snail Biomphalaria pfeifferi is the intermediate host for Schistosoma mansoni, which causes human intestinal schistosomiasis in Zimbabwe. Despite the medical importance of this intermediate host, there are no current data on its molecular characterization in Zimbabwe. In 2016, human water contact sites were identified in four communities in Madziwa area, Shamva district, Zimbabwe. The survey sites were recorded and mapped using a global positioning system. A 655 bp region of the mitochondrial cytochrome oxidase subunit I gene was amplified in 70 B. pfeifferi snails. The sequence data were analysed to determine the relationships between the individual snails, their inter, intra population diversity and structure. Overall, four unique cox1 haplotypes, with a haplotype diversity of 0.608, were identified in the snails. One haplotype spanned across most of the sites. There was no clear geographical clustering of haplotypes. The mean diversity among the haplotypes was very low (0.009), while the net divergence among the collection sites ranged from 0.000 to 0.026. The diversity within and between the sites was 0.017 and 0.012 respectively. This data advances our knowledge of the understanding of the population structure of B. pfeifferi in Madziwa area, Zimbabwe, with the high occurrence of one haplotype indicating the possibility of a recent bottleneck followed by population expansion. The population genetic structure of B. pfeifferi snails described here has provided an opportunity to investigate the contribution of snail genetics to variation in disease burden; and development of control strategies that exploit genetic differences in susceptibility to parasites.

淡水蜗牛Biomphalaria pfeifferi是曼氏血吸虫的中间宿主，曼氏血吸虫会导致津巴布韦的人类肠道血吸虫病。尽管该中间宿主具有医学重要性，但目前在津巴布韦尚无有关其分子表征的数据。2016年，在津巴布韦Shamva区Madziwa地区的四个社区中确定了人类水接触点。使用全球定位系统记录和绘制调查地点。线粒体细胞色素氧化酶亚基I基因的655 bp区域已在70株Bfeifferi蜗牛中扩增。分析序列数据以确定各个蜗牛之间，它们之间，种群内多样性和结构之间的关系。总体而言，四个独特在蜗牛中鉴定出cox 1单倍型，单倍型多样性为0.608。一种单倍型跨越大多数位点。没有明确的单体型地理集群。单倍型之间的平均差异非常低（0.009），而采集位点之间的净差异在0.000至0.026之间。位点内和位点之间的多样性分别为0.017和0.012。这些数据使我们对津巴布韦的Madziwa地区的B. pfeifferi种群结构有了更深入的了解，其中一种单倍型的发生率很高，这表明可能出现新的瓶颈，随后种群扩展。费氏芽孢杆菌的种群遗传结构这里描述的蜗牛为研究蜗牛遗传学对疾病负担变化的贡献提供了机会。以及开发利用寄生虫敏感性遗传差异的控制策略。