The aim of the current study was to investigate a possible relationship between electroconvulsive therapy (ECT) seizure adequacy parameters and clinical outcome as well as differences between ECT responders and nonresponders in terms of ECT seizure parameters in patients diagnosed with schizophrenia and schizoaffective disorder. First and last ECT records data, sociodemographic variables, and baseline and post ECT Positive and Negative Syndrome Scale scores were obtained. Maximum sustained power was higher in last ECT in favor of responders while peak heart rate was higher in ECT nonresponders than responders in first ECT. Stimulus doses were higher in last ECT than in the first ECT in both groups. No predictor variable was observed among baseline ECT seizure parameters for clinical improvement. Study was insufficient to yield a precise finding pointing a relationship between electrophysiological seizure parameters and clinical outcome in schizophrenia and schizoaffective disorder.

中文翻译：

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一项观察性回顾性研究调查精神分裂症和分裂情感性障碍电惊厥治疗癫痫发作充分参数的变化及其与临床结果的关系

本研究的目的是调查电惊厥治疗 (ECT) 癫痫充分参数与临床结果之间的可能关系，以及在诊断为精神分裂症和分裂情感障碍患者的 ECT 癫痫参数方面，ECT 反应者和无反应者之间的差异。获得了第一次和最后一次 ECT 记录数据、社会人口学变量以及基线和 ECT 阳性和阴性综合征量表评分。最后一次 ECT 的最大持续功率更高，有利于响应者，而 ECT 无响应者的峰值心率高于第一次 ECT 的响应者。两组中最后一次 ECT 的刺激剂量均高于第一次 ECT。在基线 ECT 癫痫发作参数中没有观察到临床改善的预测变量。