Abstract Dopamine is an important neurotransmitter, and nonenzyme electrochemical sensor of dopamine detection based on highly active material is urgently demanded. In this work, an electrochemical sensor with high sensitivity and selectivity based on self-rolled TiO2 microscroll/graphene composite was developed and validated for dopamine sensing. The device exhibited a superior performance for dopamine detection with a detection limit of 4.25 × 10-9 mol L-1, and in the dopamine concentration range of 0.06–90 μmol L-1, the oxidation currents increased linearly with the concentration. The remarkable performance enhancement was mainly ascribed to the increased surface area due to the porous surface of the TiO2 nanomembrane and highly conductive graphene therein. In addition, we have demonstrated that the sensor could be effectively used on detecting dopamine concentrations in urine samples. Our work demonstrates that the current microscroll-based device is promising in the field of real-time health monitoring for future human community.

中文翻译：

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用于电化学多巴胺传感的自卷 TiO2 微卷/石墨烯复合材料

摘要 多巴胺是一种重要的神经递质，迫切需要基于高活性材料的多巴胺检测非酶电化学传感器。在这项工作中，开发了一种基于自卷 TiO2 微卷/石墨烯复合材料的具有高灵敏度和选择性的电化学传感器，并验证了多巴胺传感。该装置表现出优异的多巴胺检测性能，检测限为4.25×10-9 mol L-1，在多巴胺浓度范围0.06-90 μmol L-1内，氧化电流随浓度线性增加。显着的性能提升主要归因于 TiO2 纳米膜的多孔表面和其中的高导电石墨烯增加的表面积。此外，我们已经证明该传感器可以有效地用于检测尿液样本中的多巴胺浓度。我们的工作表明，当前基于微卷的设备在未来人类社区的实时健康监测领域很有前景。