Cubic-shaped Ag3PO4 crystals with a mean size of 1 μm were synthesized by a precipitation method from a mixed solution of AgNO3, Na2HPO4, and triethanolamine. The antibacterial activities against Escherichia coli, Listeria innocua, and Pseudomonas syringae DC3000 in both the absence and presence of Ag3PO4 under dark conditions and in the presence of Ag3PO4 under red-light (625 nm) and blue-light (460 nm) irradiation were examined. The concentrations of reactive oxygen species (ROS) were also measured in the antibacterial action of the Ag3PO4 against Escherichia coli. The photoinduced enhancement of the Ag3PO4 antibacterial activity under blue-light irradiation is explained by the formation of ROS during the antibacterial action of the Ag3PO4. Moreover, the antiviral activity of Ag3PO4 against amphotropic 10A1 murine leukemia virus enhanced under blue-light irradiation via ROS production. These results provide an insight into extended bio-applications of Ag3PO4.

中文翻译：

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Ag3PO4光诱导抗菌和抗病毒活性的活性氧物种介导机制

在AgNO3、Na2HPO4和三乙醇胺的混合溶液中，通过沉淀法合成了平均尺寸为1 μm的立方形Ag3PO4晶体。检查了在黑暗条件下不存在和存在 Ag3PO4 以及在存在 Ag3PO4 的情况下在红光 (625 nm) 和蓝光 (460 nm) 照射下对大肠杆菌、无害李斯特菌和丁香假单胞菌 DC3000 的抗菌活性. 还在 Ag3PO4 对大肠杆菌的抗菌作用中测量了活性氧 (ROS) 的浓度。Ag3PO4 抗菌作用过程中 ROS 的形成解释了蓝光照射下 Ag3PO4 抗菌活性的光诱导增强。而且，Ag3PO4 对双亲性 10A1 鼠白血病病毒的抗病毒活性在蓝光照射下通过 ROS 产生增强。这些结果提供了对 Ag3PO4 的扩展生物应用的深入了解。