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Ni-Catalyzed Denitrogenative Cross-Coupling of Benzotriazinones and Cyclopropanols: An Easy Access to Functionalized β-Aryl Ketones.
Organic Letters ( IF 5.2 ) Pub Date : 2020-06-11 , DOI: 10.1021/acs.orglett.0c01579
Jincan Li 1 , Yan Zheng 1 , Mingxian Huang 1 , Wanfang Li 1
Affiliation  

A novel Ni-catalyzed denitrogenative cross-coupling between benzotriazinones and cyclopropanols is reported herein. This neoteric reactivity allows for the convenient synthesis of β-(o-amido)aryl ketones from readily available starting materials with good yields (up to 93%) and general substrate scope.

中文翻译:

苯并三嗪酮和环丙醇的镍催化脱氮交叉偶联:轻松获得功能化的β-芳基酮。

本文报道了苯并三嗪酮和环丙醇之间新型的Ni催化的脱氮交叉偶联。这种新近反应性使得可以容易地从容易获得的起始原料合成β-(氨基)芳基酮,并具有良好的收率(高达93%)和一般的底物范围。
更新日期:2020-07-02
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