Seven new modified fusicoccane-type diterpenoids (1–7), together with two known congeners (8 and 9), were obtained from Alternaria brassicicola. Their structures were elucidated from a combination of NMR and HRESIMS data and ¹³C NMR calculation as well as DP4+ probability analyses, and the absolute configurations of 1–5 were determined by ECD calculation and single-crystal X-ray diffraction (Cu Kα). Compounds 1–3 belong to a rare class of 16-nor-dicyclopenta[a,d]cyclooctane diterpenoids, and compounds 2 and 4 represent the first examples of fusicoccane-type diterpenoids featuring two previously undescribed tetracyclic 5/6/6/5 ring systems, while compound 5 features a previously undescribed tetracyclic 5/8/5/3 ring system. Compound 7 was moderately anti-inflammatory, and compounds 2, 3, 5, and 7 were weakly cytotoxic.

中文翻译：

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来自 Alternaria brasicicola 的改性 Fusicoccane 型二萜。

七新型改性fusicoccane型二萜（1 - 7）中，用两个已知的同系物（共8和9），从获得的链格孢甘蓝。其结构分别由NMR和HRESIMS数据的组合和阐明¹³ C NMR计算以及DP4 +概率分析，和的绝对构型1 - 5通过ECD计算和单晶X射线衍射（Cu靶）来测定。化合物1 - 3属于一种罕见类16-的也不-dicyclopenta [一，d ]环辛烷二萜类化合物，和化合物2图4和4代表了具有两个以前未描述的四环 5/6/6/5 环系统的岩藻烷型二萜类化合物的第一个实例，而化合物5 则具有以前未描述的四环 5/8/5/3 环系统。化合物7是适度抗炎，和化合物2，3，5，和7呈弱细胞毒性的。