Omega-3 fatty acids’ inclusion as feed supplement in the diets of both human and animals has been found to play a significant role in body metabolism. The aim of this present study was to evaluate the effects of graded doses of omega-3 fatty acids on haematology and body weight of adult male and female Rattus norvegicus (Wistar albino rats) as a model animal. A total of seventy-two adult male and female albino rats were randomly assigned into two experimental units. Each unit was grouped into three and received different treatment diets. Blood erythrocytes and weight were sampled on days 0, 14 and 28 to evaluate haematological parameters and body weight. Results showed concentration- and time-dependent significant increases (p 0.05) in the red blood cells (RBCs) and mean cell haemoglobin concentration (MCHC) in male rats after day 0. In female rats, significant increases (p 0.05) in both experimental units. Our findings depict that the use of omega-3 fatty acids in the diets of both male and female rats produced a dose-dependent effect on blood formation while its role in controlling weight gain was observed. Hence, its intake in both animal and human diets should be rightly prescribed.

中文翻译：

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Omega-3 脂肪酸作为饲料补充剂调节褐家鼠模型的血液形成和体重

Omega-3 脂肪酸作为饲料补充剂添加到人类和动物的饮食中已被发现在身体新陈代谢中发挥着重要作用。本研究的目的是评估分级剂量的 omega-3 脂肪酸对成年雄性和雌性褐家鼠（Wistar 白化大鼠）作为模型动物的血液学和体重的影响。总共七十二只成年雄性和雌性白化大鼠被随机分配到两个实验单元中。每个单元分为三个并接受不同的治疗饮食。在第 0、14 和 28 天采集血红细胞和体重样​​本，以评估血液学参数和体重。结果显示，第 0 天后雄性大鼠的红细胞 (RBC) 和平均细胞血红蛋白浓度 (MCHC) 呈浓度和时间依赖性显着增加 (p = 0.05)。在雌性大鼠中，两个实验单位均显着增加 (p = 0.05)。我们的研究结果表明，在雄性和雌性大鼠的饮食中使用 omega-3 脂肪酸对血液形成产生剂量依赖性影响，同时观察到其在控制体重增加方面的作用。因此，应正确规定其在动物和人类饮食中的摄入量。