Coordination compounds, in particular cobalt(II) mixed ligand complexes containing 1,10-phenantroline, have drawn the attention of many investigators as some of them are showing antimicrobial activities. Herein, we report three novel mixed ligand complexes of cobalt(II) having the formulae [Co(L1)2(H2O)2]Cl2, [Co(L1)2(L2)(H2O)]Cl2 and [Co2(L1)4(L2)2(L3)]Cl4 (L1 = 1,10-phenanthroline, L2 = adenine, L3 = 1,3-diaminepropane) were synthesized and characterized by elemental analysis, conductivity measurement, infrared, and UV-Vis spectroscopic techniques. Octahedral geometries are proposed to all the complexes. In vitro antibacterial activities of the ligands, salt, and metal complexes were tested on four pathogenic bacteria (Staphylococcus aureus, Salmonella typhus, Escherichia coli, and Staphylococcus epidermis) using disc diffusion method. It is interesting to note that the newly synthesized cobalt(II) complexes are active against gram negative bacteria (Escherichia coli and Klebsiella pneumoniae) even though cobalt(II) complexes are well known for their activity against gram positive bacteria.

中文翻译：

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以1,3-二氨基丙烷为间隔基的含1,10-菲咯啉和腺嘌呤的单核和双核钴（II）混合配体配合物：合成，表征和抗菌活性研究

配位化合物，特别是含有1,10-菲咯啉的钴（II）混合配体配合物，已引起许多研究者的关注，因为其中一些化合物显示出抗菌活性。本文中，我们报告了三种新型的钴（II）混合配体配合物，其分子式为[Co（L1）2（H2O）2] Cl2，[Co（L1）2（L2）（H2O）] Cl2和[Co2（L1）合成了4（L2）2（L3）] Cl4（L1 = 1,10-菲咯啉，L2 =腺嘌呤，L3 = 1,3-二胺丙烷），并通过元素分析，电导率测量，红外和UV-Vis光谱技术进行了表征。对所有配合物都提出了八面体几何形状。使用圆盘扩散法测试了四种病原菌（金黄色葡萄球菌，斑疹伤寒沙门氏菌，大肠杆菌和表皮葡萄球菌）对配体，盐和金属配合物的体外抗菌活性。