Aim: This study investigated the effects of polar Butia odorata fruit extract on metabolic, inflammatory, and oxidative stress parameters in rats submitted to a hyperlipidemia condition induced by tyloxapol. Methods: Animals were divided into 3 groups: saline, saline plus tyloxapol, and B. odorata extract plus tyloxapol. Animals were treated for 15 days with a saline solution or B. odorata fruit extract and after hyperlipidemia was induced by tyloxapol. Results: Treatment with B. odorata extract reduced serum triglyceride, total cholesterol, C-reactive protein, and adenosine deaminase and butyrylcholinesterase activities when compared to the tyloxapol group. HDL-cholesterol and paraoxonase 1 activity were higher in B. odorata extract treated animals when compared to tyloxapol-treated animals. No differences were observed in hepatic oxidative stress parameters. Phenolic compounds present in B. odorata fruit extract were identified and quantified by LC-MS/MS. Conclusion: These findings indicated that phenolic rich B. odorata extract has hypolipidemic and anti-inflammatory effects in hyperlipidemic rats.

目的：本研究探讨极地的影响，布迪椰子飞机草在提交给泰洛沙引起高脂血症大鼠条件代谢，炎症和氧化应激参数果提取物。方法：将动物分为三组：生理盐水，生理盐水加泰洛沙泊，香菇芽孢杆菌提取物加泰洛沙泊。动物进行治疗15天用生理盐水或B.飞机草果提取物和高脂血症后诱导泰洛沙。结果：用香气杆菌进行处理与泰洛沙泊组相比，提取物降低了血清甘油三酸酯，总胆固醇，C反应蛋白以及腺苷脱氨酶和丁酰胆碱酯酶的活性。高密度脂蛋白胆固醇和对氧磷酶1活性较高B.飞机草相比，泰洛沙治疗的动物时，提取处理的动物。肝氧化应激参数未见差异。通过LC-MS / MS鉴定并定量了香菇果实提取物中存在的酚类化合物。结论：这些发现表明，富含酚的香茅提取物对高脂血症大鼠具有降血脂和抗炎作用。