In article number 202000057, Tore Bengtsson and co‐workers report that oral intake of mesoporous silica particles (MSP) reduce glycated hemoglobin and low‐density lipoprotein in healthy individuals with obesity. Preclinical investigations show sequestration of pancreatic a‐amylase and lipase by MSP, suggesting that MSP lowers digestive enzymes availability in the small intestine, resulting in decreased digestion of macronutrients and reduced caloric uptake.

中文翻译：

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介孔二氧化硅颗粒：采用工程介孔二氧化硅颗粒捕获消化酶可降低人体的代谢风险因素（Adv。Healthcare Mater。11/2020）

Tore Bengtsson及其同事在文章编号202000057中报告，口服摄入中孔二氧化硅颗粒（MSP）可以减少肥胖健康个体的糖化血红蛋白和低密度脂蛋白。临床前研究表明，MSP螯合了胰腺α-淀粉酶和脂肪酶，这表明MSP降低了小肠中消化酶的利用率，从而导致大量营养物质的消化减少和热量吸收减少。