To precisely control the size of droplets produced in a flow-focusing microdroplet generator, the pressure-driven device is designed to control the flow rates of the fluids during the experiments of droplet generation. While monodisperse droplets are produced by the pressure-driven microfluidic flows, the nonlinear relation between the droplet length and the driving-pressure ratio of the two phases can be observed for the open-loop control of droplet generation. In particular, by using the method of the closed-loop control of droplet generation, good agreements are shown between the tested size of droplets and the predicted droplet size. Consequently, based on the closed-loop control of droplet generation under pressure-driven flows, the effects of the nonlinearity of the flow-focusing microchannel on the control accuracy of the droplet size is drastically reduced, which can significantly increase the control precision of the droplet size in the flow-focusing microdroplet generator.

为了精确控制在流动聚焦微滴发生器中产生的液滴的大小，压力驱动设备设计为在液滴产生实验期间控制流体的流速。当通过压力驱动的微流体流产生单分散液滴时，可以观察到液滴长度与两相的驱动压力比之间的非线性关系，以进行液滴产生的开环控制。特别地，通过使用液滴产生的闭环控制的方法，在测试的液滴尺寸和预测的液滴尺寸之间显示出良好的一致性。因此，基于压力驱动流下液滴产生的闭环控制，