We provide evidence for a linear correlation between the frequency of clonal haematopoiesis and COVID‐19 mortality rate. We discuss the mechanistic explanations for this association mediated by a pathological inflammatory response. Our hypothesis can be tested in COVID‐19‐infected patients and eventually lead to new approaches to risk stratification and therapy.

中文翻译：

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克隆性造血和 COVID-19：可能的致命联系

我们提供了克隆性造血频率与 COVID-19 死亡率之间存在线性相关性的证据。我们讨论了由病理炎症反应介导的这种关联的机制解释。我们的假设可以在 COVID-19 感染患者中进行检验，并最终导致风险分层和治疗的新方法。