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Asian Congress on Biotechnology 2019.
Biotechnology Journal ( IF 4.7 ) Pub Date : 2020-06-09 , DOI: 10.1002/biot.202000214
Min-Kyu Oh,Yasuyuki Sakai,Yu-Chen Hu

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This special issue of Biotechnology Journal is devoted to the 14th Asian Congress on Biotechnology 2019 (ACB 2019) organized by the Asian Federation of Biotechnology (AFOB) and the Biotechnology and Biochemical Engineering Society of Taiwan (BEST). ACB 2019 was held in Tamsui, New Taipei City, Taiwan, in July 1–4, 2019, and involved 5 plenary lectures and 57 academic sessions in various fields of biotechnology including topical discussion on Biotechnology for 2020 and Beyond . The congress also delivered five industrial sessions featuring the growth of bioindustry. Over a thousand participants from 32 countries around the world attended. This special issue is comprised of six reviews and six original research articles selected from the presentations.

The reviews in this issue mainly focus on technical advances in molecular biotechnology fields for sophisticated control of living organisms, for applications to emerging fields, and for sustainability of our planet. Prof. Jia Wang and colleagues summarize recent advances of synthetic biology tools based on bacterial quorum sensing system,[1] while Prof. Jeong Wook Lee and coauthors introduce various gas sensing regulators in the living organisms.[2] In some emerging areas related to biotechnology, molecular engineering tools are being developed quickly. Genetic engineering tools for lactic acid bacteria, main players in gut microbiome, are discussed.[3] Also, recent progress of biomolecular engineering tools in the field of biochips and bioelectronic devices are summarized.[4] Biotechnology has great potential to contribute to the sustainability of human society. Microorganisms that can produce biodegradable polymers or degrade the exiting plastic, which can provide solution for microplastic pollution, are summarized.[5] On the other hand, natural and synthetic microorganisms that can utilize C1 compounds as a carbon source are discussed.[6]

Three research articles report successful results of engineering in various types of living system. Overexpression of KDEL (representing lysine, aspartic acid, glutamic acid, and leucine motif) receptor 1 improved antibody production in Chinese hamster ovary (CHO) cells.[7] A CO2‐driven syntrophic consortium of two engineered bacteria succeeded in conversion of 5‐hydroxymethylfurfural, a biomass‐derived byproduct, to 2,5‐furandicarboxylic acid.[8] A conversion of xylose to xylitol was demonstrated using light‐driven reducing power in cyanobacteria.[9] The other three articles present useful tools or new findings that can be used in various biotechnology fields. Metabolic fluxes of engineered bacteria to overproduce gamma‐aminobutyrate were successfully monitored using 13C metabolic flux analysis.[10] Software performances for template‐based protein structure modeling were compared using thousands of structural dataset.[11] Also, characterization of oxygen sensing mechanism of ArcA in Escherichia coli was attempted.[12]

In this special issue of Biotechnology Journal , two forum articles were specially added to cover timely and urgent problem we met in all over the world, which is pandemic COVID‐19. The first article explains the molecular composition and characterization of the virus, molecular targets for detection and diagnosis, social ethics, etc.[13] The second article introduces the scientific background for COVID‐19 vaccine development.[14]

We hope this pandemic situation is eased or ended soon with the development of vaccine and therapeutics. In next year, 15th Asian Congress on Biotechnology (ACB 2021) is being organized by the Asian Federation of Biotechnology, with the schedule and venue at July 4–8, 2021 in Bali, Indonesia. We anticipate to have another prosperous meeting together in Bali next year.

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Prof. Min‐Kyu Oh

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Prof. Yasuyuki Sakai

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Prof. Yu‐Chen Hu

更新日期:2020-06-09
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