The vagus nerve has anti‐inflammatory properties. We aimed to investigate vagus nerve stimulation (VNS) as a new therapeutic strategy targeting an intrinsic anti‐inflammatory pathway in a pilot study in Crohn's disease patients. The main objectives addressed the questions of long‐term safety, tolerability, and anti‐inflammatory effects of this therapy. This study is the continuation of previous reported findings at 6 months.

中文翻译：

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克罗恩病迷走神经刺激的 12 个月初步研究结果。

迷走神经具有抗炎特性。我们旨在研究迷走神经刺激 (VNS) 作为一种针对克罗恩病患者的初步研究中的内在抗炎途径的新治疗策略。主要目标解决了该疗法的长期安全性、耐受性和抗炎作用等问题。本研究是先前报告的 6 个月研究结果的延续。