Special hormonal and immunological changes are required for normal pregnancy continuation. To escape from rejection by the maternal immune system, pregnancy needs an optimum environment with the integration and the balance of immune factors. As an immunologically unique site that permits allogenic fetus to be tolerated by mother, the maternal–fetal interface has a vital role. Microorganisms may trigger innate immune responses at the maternal–fetal interface and this may have a significant impact on the success of pregnancy. While the presence of inflammatory markers are slightly increased in healthy pregnancies, their significant increase in preeclampsia suggests that the balance between the inflammatory and antiinflammatory mechanisms may be disrupted by a shift towards inflammation. Based on these immunological observations, we aimed to review the literature for the link between the inflammatory response and preeclampsia since its etiology has not yet been clarified.

中文翻译：

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子痫前期循环炎症分子的增加，这是一种更新。

正常的妊娠继续需要特殊的激素和免疫学改变。为了摆脱母体免疫系统的排斥，怀孕需要一个具有免疫因子整合和平衡的最佳环境。作为一个免疫学上独特的位点，母亲可以耐受异体胎儿，因此母婴界面起着至关重要的作用。微生物可能会触发母婴界面的先天性免疫反应，这可能对怀孕的成功产生重大影响。尽管健康孕妇中炎症标记物的存在量略有增加，但先兆子痫的明显增加表明炎症和抗炎机制之间的平衡可能会因向炎症的转变而受到破坏。基于这些免疫学观察，