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Transitional Locomotor Tasks in People With Mild to Moderate Parkinson's Disease.
Frontiers in Neurology ( IF 3.4 ) Pub Date : 2020-05-15 , DOI: 10.3389/fneur.2020.00405
Anna Kamieniarz 1 , Justyna Michalska 1 , Wojciech Marszałek 1 , Anna Akbaş 1 , Kajetan J Słomka 1 , Agnieszka Krzak-Kubica 2 , Monika Rudzińska-Bar 3 , Grzegorz Juras 1
Affiliation  

Background: People with Parkinson's disease (PD) exhibit deficits in maintaining balance both during quiet standing and during walking, turning, standing up from sitting, and step initiation. Objective: The purpose of this study was to examine balance disorders during a transitional task under different conditions in participants with PD. Methods: The research was conducted on 15 PD-II (mild) and 15 PD-III (moderate) individuals (H&Y II-III stage) and 30 healthy elderly. The transitional task was measured on two force platforms (A and B). The procedure consisted of three phases: (1) quiet standing on platform A, (2) crossing to platform B, and (3) quiet standing on platform B, each until measurements were completed. There were four conditions: crossing without an obstacle, crossing with an obstacle, and walking up and down the step. Results: There were no significant differences between mild PD individuals and healthy elderly during quiet standing before the transitional task and after completing the task. The temporal aspects describing the different transitional tasks were comparable between mild PD and healthy subjects. Moderate PD participants presented a significantly higher COP velocity after the transitional task compared to the healthy older adults (p < 0.05). Additionally, the moderate PD group showed significantly higher values for transit time relative to healthy subjects during the transitional task in all conditions (p < 0.05). Conclusions: Disease severity affects the temporal aspects of different transitional tasks in people with PD. The procedure of completing a transitional task under different conditions allowed differences between moderate and mild PD stages and healthy subjects to be observed.

中文翻译:

轻度至中度帕金森病患者的过渡性运动任务。

背景:帕金森病 (PD) 患者在安静站立、行走、转身、从坐站起来和开始迈步时都表现出维持平衡的缺陷。目的:本研究的目的是检查 PD 参与者在不同条件下过渡任务期间的平衡障碍。方法:该研究对 15 名 PD-II(轻度)和 15 名 PD-III(中度)个体(H&Y II-III 期)和 30 名健康老年人进行。过渡任务在两个力量平台(A 和 B)上进行测量。该程序包括三个阶段:(1) 安静地站在平台 A 上,(2) 穿过平台 B,以及 (3) 安静地站在平台 B 上,每个阶段直到测量完成。有四种情况:无障碍穿越、有障碍穿越、上下台阶。结果:轻度PD个体与健康老年人在过渡任务前和完成任务后的安静站立方面没有显着差异。描述不同过渡任务的时间方面在轻度帕金森病和健康受试者之间具有可比性。与健康老年人相比,中度 PD 参与者在过渡任务后表现出显着更高的 COP 速度 (p < 0.05)。此外,在所有条件下的过渡任务期间,中度 PD 组的过渡时间值均显着高于健康受试者 (p < 0.05)。结论:疾病严重程度影响 PD 患者不同过渡任务的时间方面。在不同条件下完成过渡任务的过程可以观察到中度和轻度PD阶段以及健康受试者之间的差异。
更新日期:2020-05-15
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