This review aims to summarize the last advances on the field of protein engineering towards functional bionanomaterials. Albeit being this an emerging research field, multidisciplinary perspectives in the design of synthetic protein-based hybrid bionanomaterials have resulted in significant progresses. The review covers the definition of bionanomaterials as such and the description of the main methodological approaches currently employed for their assembly. In this context, special emphasis is placed on the fundamental role of protein design. Then, a general overview of the most recent advances related to the fabrication and application of protein-based bionanomaterials in several applications is provided, with special focus on catalysis. Finally, key aspects to be considered by the research community to establish the path for significant future developments in this promising field are discussed.

中文翻译：

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通过自下而上的方法开发基于蛋白质的功能性杂化生物纳米材料。

本综述旨在总结蛋白质工程领域对功能性生物纳米材料的最新进展。尽管这是一个新兴的研究领域，但基于合成蛋白质的混合生物纳米材料设计的多学科视角已经取得了重大进展。该评论涵盖了生物纳米材料本身的定义以及目前用于其组装的主要方法学方法的描述。在这种情况下，特别强调蛋白质设计的基本作用。然后，概述了与蛋白质基生物纳米材料在多种应用中的制造和应用相关的最新进展，特别关注催化。最后，