Carbohydrates play important roles in life science, but their synthesis is always hampered by their complicated chemical structures. Scientists have never stopped trying to solve the problem of glycan synthesis from various aspects. Here a brief overview of recent progress in glycan synthesis, including chemical approaches, chemoenzymatic approaches, and automated synthesis, will be discussed, focusing on the efficiency of new glycosylation methods, the stereoselectivity of coupled products, and their applications in the assembly of complex glycan chains.

中文翻译：

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聚糖合成的最新进展。

碳水化合物在生命科学中发挥着重要作用，但它们的合成总是受到其复杂化学结构的阻碍。科学家们从未停止尝试从各个方面解决聚糖合成问题。这里将简要概述聚糖合成的最新进展，包括化学方法、化学酶法和自动合成，重点是新糖基化方法的效率、偶联产物的立体选择性及其在复杂聚糖组装中的应用链。