Hydrophilic polyacrylamide gel-based triazine-type condensing reagents, PAG-Trz-Cl, have been developed. PAG-Trz-Cls were synthesized using a chlorotriazine with an acrylamide moiety, acrylamide, and N,N'-methylenebisacrylamide via both precipitation and solution polymerization. Because PAG-Trz-Cls adequately swell in aqueous media, the amidation between polar carboxylic acids and amines afforded the corresponding amides in good yields.

中文翻译：

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含氯三嗪的亲水性聚丙烯酰胺凝胶缩合试剂的开发。

已经开发了基于亲水性聚丙烯酰胺凝胶的三嗪型缩合剂PAG-Trz-Cl。使用具有丙烯酰胺部分，丙烯酰胺和N，N'-亚甲基双丙烯酰胺的氯三嗪通过沉淀和溶液聚合合成PAG-Trz-Cls。因为PAG-Trz-Cls在水性介质中充分溶胀，所以极性羧酸和胺之间的酰胺化反应以高收率提供了相应的酰胺。