Objective: The benefits of carpal tunnel decompressive surgery (CTDS) among diabetic patients with carpal tunnel syndrome (CTS) were previously investigated through comparing the outcome before and after CTDS, and in comparison to nondiabetic CTS. We sought to investigate if diabetes mitigates the benefits of CTDS compared to not receiving CTDS. Methods: In this retrospective study, we compared the risk of reporting any unfavorable outcomes among CTS patients (diabetic and nondiabetic) who underwent CTDS versus no CTDS after controlling for diabetes. We also compared the risk of reporting any unfavorable outcomes (waking up at night, pain during the day or during daily activities, or hand weakness) among diabetic CTS patients who underwent CTDS versus no CTDS after controlling for severity. Results: We included 207 patients; of these, 105 patients had CTDS and 102 did not. There were 60 diabetic and 147 nondiabetic patients. The risk of any unfavorable outcomes was reduced by CTDS from 83.3 to 66.6%, with an odds ratio (OR), after controlling for diabetes, of 0.39 (95% confidence interval [CI] 0.20–0.78). Among diabetic patients, there was no difference between the CTDS and non-CTDS groups in the risk of reporting any unfavorable outcomes; however, after adjustment for severity, the risk of hand weakness was less with CTDS, with an OR of 0.13 (95% CI 0.02–0.86). Conclusion: Diabetes did not mitigate the benefits of CTDS. CTDS may prevent hand weakness among diabetic CTS patients.

中文翻译：

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腕管减压手术对糖尿病的疗效及效果

目的：先前通过比较 CTDS 前后的结果以及与非糖尿病 CTS 的比较，研究了腕管减压手术 (CTDS) 在患有腕管综合征 (CTS) 的糖尿病患者中的益处。我们试图调查与不接受 CTDS 相比，糖尿病是否减轻了 CTDS 的益处。方法：在这项回顾性研究中，我们比较了在控制糖尿病后接受 CTDS 与未接受 CTDS 的 CTS 患者（糖尿病和非糖尿病）报告任何不利结果的风险。我们还比较了在控制严重程度后接受 CTDS 与未接受 CTDS 的糖尿病 CTS 患者报告任何不利结果（夜间醒来、白天或日常活动时疼痛或手无力）的风险。结果：我们纳入了 207 名患者；这些，105 名患者有 CTDS，102 名没有。有 60 名糖尿病患者和 147 名非糖尿病患者。CTDS 将任何不利结果的风险从 83.3% 降低到 66.6%，控制糖尿病后的优势比 (OR) 为 0.39（95% 置信区间 [CI] 0.20-0.78）。在糖尿病患者中，CTDS 组和非 CTDS 组在报告任何不利结果的风险方面没有差异；然而，在调整严重程度后，CTDS 手部无力的风险较低，OR 为 0.13（95% CI 0.02–0.86）。结论：糖尿病并没有减轻 CTDS 的益处。CTDS 可以预防糖尿病 CTS 患者的手部无力。控制糖尿病后，为 0.39（95% 置信区间 [CI] 0.20–0.78）。在糖尿病患者中，CTDS 组和非 CTDS 组在报告任何不利结果的风险方面没有差异；然而，在调整严重程度后，CTDS 手部无力的风险较低，OR 为 0.13（95% CI 0.02–0.86）。结论：糖尿病并没有减轻 CTDS 的益处。CTDS 可以预防糖尿病 CTS 患者的手部无力。控制糖尿病后，为 0.39（95% 置信区间 [CI] 0.20–0.78）。在糖尿病患者中，CTDS 组和非 CTDS 组在报告任何不利结果的风险方面没有差异；然而，在调整严重程度后，CTDS 手部无力的风险较低，OR 为 0.13（95% CI 0.02–0.86）。结论：糖尿病并没有减轻 CTDS 的益处。CTDS 可以预防糖尿病 CTS 患者的手部无力。