Significant progress attained in sensor science in recent years has resulted in the development of highly efficient fluorescence probes for sensing metal ions. Fluorescent molecular probes based on (R)‐(−)‐4‐phenyl‐2‐oxazolidone are reported here. Fluorescence studies indicated that the molecular probe could be used successfully to sense divalent metal cations such as Cu²⁺, Co²⁺, Pb²⁺, and Zn²⁺. The addition of divalent metal cations to the molecular probe produced a specific interaction pattern under UV–visible and fluorescence spectroscopy. These molecules could detect metal cations using fluorescence quenching. Stern–Volmer plots were used to determine quenching rate coefficients, which were calculated to be 2 × 10¹, 1.06 × 10³ and 7.39 × 10² M⁻¹ s⁻¹ for copper, cobalt, and zinc respectively. Calculation of limit of detection for heavy metal cations revealed that the reported molecular probes improved the limit of detection compared with available standard data. Limit of quantitation values were also well within the permissible range. The frontier energy gap of highest occupied molecular orbital to the lowest unoccupied molecular orbital was evaluated using the density functional theory approach and Gaussian 09 W software, which complemented the coordination of azetidinones with divalent metal ions.

中文翻译：

---

基于（R）-（-）-4-苯基-2-恶唑烷酮的荧光探针传感器，可有效检测二价阳离子。

近年来，传感器科学领域取得了重大进展，导致了用于感测金属离子的高效荧光探针的开发。本文报道了基于（R）-（-）-4-苯基-2-恶唑烷酮的荧光分子探针。荧光研究表明，该分子探针可以成功地用于检测二价金属阳离子，例如Cu 2 ⁺，Co 2 ⁺，Pb ²⁺和Zn ²⁺。在分子探针上添加二价金属阳离子在紫外可见光谱和荧光光谱下产生了特定的相互作用模式。这些分子可以使用荧光猝灭检测金属阳离子。Stern-Volmer图用于确定淬灭速率系数，计算得出为2×10 ¹对于铜，钴和锌，分别为1.06×10 ³和7.39×10 ² M ^-1 s ^-1。计算重金属阳离子的检出限表明，与现有的标准数据相比，报道的分子探针提高了检出限。定量限值也很好地在允许范围内。使用密度泛函理论方法和高斯09 W软件评估了最高占据分子轨道到最低未占据分子轨道的前沿能隙，该方法补充了氮杂环丁酮与二价金属离子的配位作用。