Migratory dendritic cells (DCs) in tumors transport antigens and share them with lymph node resident DCs through cross-presentation. In this issue of Cancer Cell, Ruhland et al. demonstrate that transport and transfer of tumor antigens in vesicles is a dominant pathway to load resident DCs for presentation to T cells.

中文翻译：

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肿瘤抗原的交叉呈递由树突状细胞亚群中囊泡的突触转移决定。

肿瘤中的迁移树突状细胞 (DC) 运输抗原，并通过交叉呈递与淋巴结驻留的 DC 共享抗原。在本期《癌细胞》中，Ruhland 等人。证明囊泡中肿瘤抗原的运输和转移是加载常驻 DC 并呈递给 T 细胞的主要途径。