Stroke is induced by a partial disruption of cerebral blood flow to the brain and is related to high morbidity and mortality. In the central nervous system, exosomes have been proven to exert neuroprotective effects, reducing brain damage following a stroke. This review was performed by searching the relevant articles in the SCIENCEDIRECT, PUBMED, and Web of Science databases from respective inception to November 2018. We review the relationship between exosomes and angiogenesis, neurogenesis, antiapoptosis, autophagy, and the blood–brain barrier in stroke. Moreover, exosomes are found to be a promising tool for the diagnosis and treatment of stroke. In summary, exosomes provide a novel way to alleviate brain damage following a stroke.

中风是由流向大脑的脑血流部分中断引起的，并且与高发病率和死亡率有关。在中枢神经系统中，外泌体已被证明具有神经保护作用，可减少中风后的脑损伤。这篇综述是通过搜索 SCIENCEDIRECT、PUBMED 和 Web of Science 数据库中从各自成立到 2018 年 11 月的相关文章进行的。我们回顾了外泌体与血管生成、神经发生、抗细胞凋亡、自噬和中风血脑屏障之间的关系. 此外，发现外泌体是诊断和治疗中风的有前途的工具。总之，外泌体提供了一种减轻中风后脑损伤的新方法。