Oxadiazole moiety, which is one of the heterocyclic aromatic groups of the azole family; with the molecular formula C2H2N2O, exists in four isomeric form; out of which, 1,2,4-oxadiazole; 1,2,5-oxadiazole and 1,3,4-oxadiazole are common isomers. The stable isomeric forms of oxadiazoles are observed in a variety of pharmaceutical important potent drugs including raltegravir, butalamine, fasiplon, oxolamine and pleconaril. An attempt has been made to emphasize the chemistry and pharmacology associated with oxadiazole and its derivatives. A number of oxadiazole derivatives are very popular and common in use as potential therapeutic agents. However, a number of researchers are working and have worked to find out more synthetic analogues for anticancer and antifungal, anti-HIV agents using biological and in-silico models.

恶二唑部分，是唑族的杂环芳族基团之一；分子式为C2H2N2O，存在四种异构形式。其中1,2,4-恶二唑; 1,2,5-恶二唑和1,3,4-恶二唑是常见的异构体。恶二唑的稳定异构体形式可在多种重要的药物中观察到，包括拉格韦，丁胺，法西隆，草胺和普康那利。已经尝试强调与恶二唑及其衍生物有关的化学和药理学。许多恶二唑衍生物非常流行并普遍用作潜在的治疗剂。但是，许多研究人员正在使用生物模型和计算机模拟模型来寻找更多的用于抗癌和抗真菌，抗HIV药物的合成类似物。