Psoriasis is a common inflammatory disease that can involve the skin, joints, or both. The abnormalities of innate immunity play crucial roles in the pathogenesis of psoriasis. Neutrophils are the most abundant leukocytes in the circulation. Emerging evidences have demonstrated that neutrophils may play a role in autoimmune diseases. The neutrophil-to-lymphocyte ratio (NLR), the activity of neutrophils, and the number of NETotic cells were significantly higher in psoriasis patients compared to healthy controls. The number of low-density granulocytes (LDGs) in the blood of psoriasis patients was significantly higher than those in the control blood. Furthermore, neutrophils may play important roles in the cardiovascular risk in psoriasis. However, the exact role of neutrophils in psoriasis remains unclear. In this review, we highlight the role of neutrophils in the pathogenesis of psoriasis.

中文翻译：

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中性粒细胞在牛皮癣中的作用。

牛皮癣是一种常见的炎症性疾病，可能涉及皮肤，关节或两者。先天免疫的异常在牛皮癣的发病机理中起关键作用。中性粒细胞是循环中最丰富的白细胞。新兴证据表明，中性粒细胞可能在自身免疫性疾病中起作用。与健康对照组相比，牛皮癣患者的中性粒细胞与淋巴细胞之比（NLR），中性粒细胞活性和NETotic细胞数量显着更高。银屑病患者血液中低密度粒细胞（LDG）的数量显着高于对照血液中的低密度粒细胞（LDG）的数量。此外，中性粒细胞可能在牛皮癣的心血管风险中起重要作用。然而，尚不清楚中性粒细胞在牛皮癣中的确切作用。在这篇评论中