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The use of eugenol in combination with cefotaxime and ciprofloxacin to combat ESBL-producing quinolone-resistant pathogenic Enterobacteriaceae.
Journal of Applied Microbiology ( IF 4 ) Pub Date : 2020-06-05 , DOI: 10.1111/jam.14737
L Dhara 1 , A Tripathi 1
Affiliation  

Emergence of extended‐spectrum beta‐lactamase (ESBL) producing with quinolone‐resistant (QR) pathogenic Enterobacteriaceae augmented the need to establish therapeutic options against them. Present study aimed towards determination of synergistic combination of eugenol (EG) with cefotaxime (CTX) and ciprofloxacin (CIP) to combat against this resistance and potentiation of antibacterial drugs by EG against these bacteria.

中文翻译:

丁香酚与头孢噻肟和环丙沙星的组合用于对抗产生ESBL的喹诺酮耐药性致病性肠杆菌科。

喹诺酮耐药性(QR)致病性肠杆菌科细菌产生的广谱β-内酰胺酶(ESBL)的出现增加了建立针对它们的治疗选择的需求。目前的研究旨在确定丁香酚(EG)与头孢噻肟(CTX)和环丙沙星(CIP)的协同组合,以对抗这种耐药性以及EG对这些细菌的抗菌药增强作用。
更新日期:2020-06-05
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