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Thymus aging in mice deficient in either EphB2 or EphB3, two master regulators of thymic epithelium development.
Developmental Dynamics ( IF 2.5 ) Pub Date : 2020-06-07 , DOI: 10.1002/dvdy.212 Javier García-Ceca 1, 2 , Sara Montero-Herradón 1, 2 , Agustín G Zapata 1, 2
Developmental Dynamics ( IF 2.5 ) Pub Date : 2020-06-07 , DOI: 10.1002/dvdy.212 Javier García-Ceca 1, 2 , Sara Montero-Herradón 1, 2 , Agustín G Zapata 1, 2
Affiliation
The epithelial microenvironment is involved in thymus aging, but the possible role of EphB receptors that govern the thymic epithelium development has not been investigated. Herein, we study the changes undergone by the thymus of EphB‐deficient mice throughout their life.
中文翻译:
缺乏 EphB2 或 EphB3(胸腺上皮发育的两个主要调节因子)的小鼠的胸腺衰老。
上皮微环境与胸腺衰老有关,但尚未研究控制胸腺上皮发育的 EphB 受体的可能作用。在此,我们研究了 EphB 缺陷小鼠的胸腺在其一生中所经历的变化。
更新日期:2020-06-07
中文翻译:
缺乏 EphB2 或 EphB3(胸腺上皮发育的两个主要调节因子)的小鼠的胸腺衰老。
上皮微环境与胸腺衰老有关,但尚未研究控制胸腺上皮发育的 EphB 受体的可能作用。在此,我们研究了 EphB 缺陷小鼠的胸腺在其一生中所经历的变化。