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The mechanical properties and bactericidal degradation effectiveness of tannic acid-based thin films for wound care.
Journal of the Mechanical Behavior of Biomedical Materials ( IF 3.9 ) Pub Date : 2020-06-07 , DOI: 10.1016/j.jmbbm.2020.103916
B Kaczmarek 1 , M Wekwejt 2 , K Nadolna 1 , A Owczarek 1 , O Mazur 1 , A Pałubicka 3
Affiliation  

The surface area is the most important aspect when considering the interactions between a material and the surrounding environment. Chitosan (CTS) and tannic acid (TA) were previously successfully tested by us to obtain thin films to serve as wound dressings or food packaging materials. However, surface properties as well as the antimicrobial activity of the material were not considered. They are important if the material is likely to find application in biomedical or food packaging application. Thereby, this study is a further investigation of chitosan/tannic acid films surface properties.

The results showed that higher content of tannic acid increases the surface free energy and roughness, which is beneficial when considering the application of the materials as wound dressings. However, higher content of chitosan provides better antibacterial properties. Hence, the most optimal complex of chitosan and tannic acid for proposed application is the ratio 80/20.



中文翻译:

单宁酸基薄膜在伤口护理方面的机械性能和杀菌降解效果。

当考虑材料与周围环境之间的相互作用时,表面积是最重要的方面。壳聚糖(CTS)和单宁酸(TA)先前已由我们成功测试过,以获得用作伤口敷料或食品包装材料的薄膜。然而,没有考虑材料的表面性质以及抗微生物活性。如果该材料很可能在生物医学或食品包装中得到应用,则它们非常重要。因此,这项研究是对壳聚糖/单宁酸膜表面性能的进一步研究。

结果表明,较高的鞣酸含量会增加表面自由能和粗糙度,这在考虑将这种材料用作伤口敷料时是有益的。但是,较高的壳聚糖含量可提供更好的抗菌性能。因此,对于建议的应用,壳聚糖和单宁酸的最佳最佳配合物为80/20。

更新日期:2020-06-07
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