Ageing Research Reviews ( IF 13.1 ) Pub Date : 2020-06-06 , DOI: 10.1016/j.arr.2020.101094 Brenna Osborne 1 , Daniela Bakula 1 , Michael Ben Ezra 1 , Charlotte Dresen 1 , Esben Hartmann 1 , Stella M Kristensen 1 , Garik V Mkrtchyan 1 , Malte H Nielsen 1 , Michael A Petr 1 , Morten Scheibye-Knudsen 1
Ageing is arguably the most complex phenotype that occurs in humans. To understand and treat ageing as well as associated diseases, highly specialised technologies are emerging that reveal critical insight into the underlying mechanisms and provide new hope for previously untreated diseases. Herein, we describe the latest developments in cutting edge technologies applied across the field of ageing research. We cover emerging model organisms, high-throughput methodologies and machine-driven approaches. In all, this review will give you a glimpse of what will be pushing the field onwards and upwards.
中文翻译:
老化研究的新方法。
可以说,衰老是人类中最复杂的表型。为了理解和治疗衰老以及相关疾病,新兴的高度专业化技术揭示了对潜在机制的关键见识,并为以前未治疗的疾病提供了新希望。在此,我们将介绍在老化研究领域中应用的尖端技术的最新发展。我们涵盖新兴的模型生物,高通量方法论和机器驱动的方法。总而言之,本次审查将使您了解将推动该领域向前和向上发展的因素。